Multiple sclerosis: new study highlights five warning signs of the disease – December 06, 2023
What if the biological mechanisms that cause multiple sclerosis were triggered years before clinical diagnosis? This is what a team at Paris Brain Institute suggests in a new study published in Neurology. The researchers show that, on a population scale, the frequency of disorders such as depression, constipation, and urinary tract infections is associated with a diagnosis of multiple sclerosis five years later. These results outline a prodromal phase of the disease, but at this stage, they do not allow for the development of an early detection technique.
The art of wandering in vertebrates: new mapping of neurons involved in locomotion – September 04, 2023
Walking is a complex mechanism involving both automatic processes and conscious control. Its dysfunction can have multiple, sometimes extremely subtle causes, within the motor cortex, brain stem, spinal cord, or muscles. At Paris Brain Institute, Martin Carbo-Tano, Mathilde Lapoix, and their colleagues in the “Spinal Sensory Signaling” team, led by Claire Wyart (Inserm), have focused on a specific component of locomotion: forward propulsion. In a study published in Nature Neuroscience, they show that it involves a region classically called the mesencephalic locomotor region, which controls the vigor and speed of movement, and transmits the nervous message to the spinal cord via control neurons located in the brainstem.
A simple blood test can now diagnose De Vivo disease – June 06, 2023
How does the visual cortex adapt to the recognition of words written with different characters? To answer this question, Laurent Cohen at Paris Brain Institute and the Unicog team led by Stanislas Dehaene at NeuroSpin, CEA’s neuroimaging center, studied the brains of 31 bilingual people.
In bilingual readers, the visual cortex processes Latin and Chinese characters differently – April 11, 2023
How does the visual cortex adapt to the recognition of words written with different characters? To answer this question, Laurent Cohen at Paris Brain Institute and the Unicog team led by Stanislas Dehaene at NeuroSpin, CEA’s neuroimaging center, studied the brains of 31 bilingual people.
Sensory cells taste the cerebrospinal fluid to fight brain infections – February 15, 2023
Sensory neurons capture information from our senses and communicate it to the central nervous system. But this is not their only mission. In a new study published in the journal Current Biology, Claire Wyart, Inserm research director at the Institut du Cerveau, and Christina Vandenbroucke-Grauls, at the University Medical Center of Amsterdam, have shown that these neurons play a key role in pneumococcal meningitis, a serious infection with high mortality and epidemic potential: they help fight the infection and promote host survival.
Towards better management of disinhibition in frontotemporal dementia – January 30, 2023
Disinhibition is one of the main symptoms of the behavioural variant frontotemporal dementia (bvFTD), a type of dementia associated with degeneration of the frontal and temporal lobes of the brain. Patients with bvFTD exhibit behaviours that are considered inappropriate, to the point that caregivers and family members may feel helpless.
L’Institut du Cerveau signe l’acquisition d’un IRM 7 Tesla et d’un IRM 3 Tesla – December 15, 2023
The work of Professor Fanny Mochel (AP-HP, Sorbonne University) at Paris Brain Institute, in collaboration with clinical research teams in eight countries and Spanish biotech Minoryx Therapeutics, has demonstrated the protective effects of leriglitazone in the progression of adrenoleukodystrophy – a rare genetic disease in which the white matter of the central nervous system is damaged.
Institut du Cerveau – ICM AND FONDATION ABEONA PARTNER ON TWO ARTIFICIAL INTELLIGENCE PROJECTS THAT WILL ADVANCE GENDER EQUALITY
BRAiN’US : aidez les chercheurs à faire connaissance avec vous
L’Institut du Cerveau et de la Moelle Epinière, Centre d’excellence dans la lutte contre les maladies neurodégénératives
Le vêtement intelligent qui révolutionne le diagnostic médical
Les 20 kms de Paris (2014)
Quand respirer nous libère l’esprit
Le premier laboratoire commun de recherche en e-santé, BRAIN e-NOVATION
Découverte d’un gêne responsable d’épilepsies focales
“Signature cérébrale de la conscience” par Lionel Naccache
INSIGHT, une étude innovante sur la maladie d’Alzheimer