PHENO-ICMice : rodent preclinical phenotyping service

The Rodent Service is a 1500 sqm facility in Paris dedicated to research on new rodent models of human diseases and their use in preclinical studies. The facility supplies state of the art equipment and specialized staff to academics and industrials. With 7000 ventilated cages, both SOPF and SPF housing areas are provided, including ABSL1 and ABSL2 and 40 equipped procedure rooms. A well-established outsource company is in charge of animal care. PHENO-Institut du Cerveau – ICMice is part of the Institut du Cerveau – ICM core facility network (small animal MRI, sequencing, vectorology, histology, microscopy…) which facilitates translational research.

ACTIVITIES

• Rodent Behavior:
locomotion, anxiety, depression, memory, sociability…
• Rodent Surgery:
stereotactic surgery, live imaging, electroporation, tissue harvest…
• Rodent Neurophysiology:
EEG, EMG, evoked potentials, optogenetics…
• Renting of procedure rooms
• Consulting

PROCEDURE ROOMS

• 12 for behavioral tests
• 12 for surgery (binoculars, microscopes, stereotaxy frames,
electrodes)
• 11 for experimentation (PSM,
binoculars, microscopes, electrodes)

EQUIPMENT

• Housing capacity: 7000 cages
3000 ventilated cages SPF
4000 ventilated cages SOPF
• Automated cage wash system
• Biosafety level
ABSL 1
ABSL 2
• 40 equipped procedure rooms
• Restricted access
• 11.7T MRI

ANIMAL CARE

(Ethical respect of 3R rules)
• Breeding
• Plugging
• Weaning
• Tissue harvest-genotyping
• Tattooing
• Cleaning-feeding

TEAM

Brahim Nait Oumesmar —Scientific advisor
Magali Dumont —Head
Doriane Foret —Behavior manager
Anne-Laure Privat —Surgery manager
Delphine Roussel —Neurophysiology manager

CONTACT

pheno-icmice@icm-institute.org