Bio-informatics core facility
Scientific manager: Stanley DURRLEMAN (PhD, DR2, INRIA)
Operational manager: Ivan MOSZER (PhD)
The iCONICS platform is running three types of activities: “Databases and Datawarehouse”, “Genomics/ Bioinformatics” and “Biostatistics”. The “Databases and Datawarehouse” division develops databases with secure web interfaces, supported by a shared data model that covers a variety of domains (e.g., clinics, biology, genetics, images…). Data is then cross-referenced in a datawarehouse to visualize dynamic reports. The “Genomics/Bioinformatics” division builds and runs pipelines to process and interpret a range of genetics and (epi) genomics data, from high-throughput sequencing analyses (e.g., wholeexome sequencing, RNA-seq, Methyl-seq) and array analyses (e.g. GWAS). The “Biostatistics” division provides basic support in statistical data analysis and designs advanced statistical methods to deal with the integrative analysis of high-dimensional and multimodal data. The platform provides scientists and physicians with both an analytical support (study design, data processing and interpretation) and Webbased services (e.g. transcriptomics data exploration, brain lesion characterization from neuroimaging data).